Jilu Jaffet, mentored by Dr Vivek Singh, Dr Sayan Basu & Prof Javed Ali, was awarded the PhD for her work titled, ‘Optimizing and characterizing mesenchymal stem cells derived from the human lacrimal gland and their secretome for potential therapeutic applications in dry eye disease’.
Her study explores the therapeutic potential of the secretome of the mesenchymal stem cells derived from the human lacrimal gland. Using advanced proteomics and functional assays, the research identifies key components that can support lacrimal gland repair. Reflecting on the significance of the work, Jilu says, 'The study offers a basis for cell-free therapy to treat dry eyes, offering hope to many patients.'
Dry Eye Disease is a widespread condition that often relies on short-term treatments. The study reveals how lacrimal gland-derived mesenchymal stem cell secretome helps the lacrimal gland heal itself, by opening survival pathways and reducing damage, offering a more long-lasting treatment for dry eyes.
