Basic Research

Basic Research - KAR & MTC Campus

S. No. Title Funding Agency Duration Principal Investigator
1 Effect of maternal diabetes during pregnancy on placental epigenetics and its association with retinal development and risk of retinopathy in infantsWellcome Trust India Alliance early career fellowship2024-2029Dr Aatish Mahajan
2Impact of Urban Air Pollution on ocular surface microbiome changes and its effect on dry eye disease Indian Council of Medical Research 2021-2025Dr Arunasri Kotakonda
3Mitochondrial Association with Transcriptomic Signatures for Trabecular Meshwork Damage in Glaucoma: A tissue-specific omics approach Indian Council of Medical Research 2025-2027Dr Aparna Rao
4 Setting up pathogen surveillance systems beyond SARS-CoV2 Rockefeller Foundation2022-2025Dr Bhupesh Bagga
5 Role of TRP ion channels in regulating corneal endothelial response to increased intraocular pressure Science and Engineering Research Board2023-2026Dr Charanya Ramachandran
6Silk Fibroin carrier for the culture and transplantation of corneal endotheliumDepartment of Biotechnology 2024-2027 Dr Charanya Rmachandran
7Identification of diagnostic biomarkers in vitreous/ aqueous fluid of ocular tuberculosis patients.Indian Council of Medical Research 2023-2026 Dr Himanshu Behera
8Investigating a crystiInvestigating a-crystallin-particulate matter interactions to assess the impact of air pollution on ocular protein homeostasis Indian Council of Medical Research 2023-2026Dr Inderjeet Kaur
9Development of intraocular implant providing controlled and localized combination drug therapy- towards efficacious treatment of diabetic retinopathyIndian Council of Medical Research 2023-2026Dr Inderjeet Kaur
10 Sustained dual drug release of Timolol Maleate and Latanoprost for Glaucoma Treatment: In vivo studies towards cross-linker free drug-polymer formulation for usage as eye drop Indian Council of Medical Research 2025-2028Dr Inderjeet Kaur
11Generation and evaluation of universal donor stem cells for applications in allogenic cell therapy for retinal dystrophic conditions Indian Council of Medical Research 2022-2025 Dr Indumathi Mariappan
12 Clinical utility of Extracellular Vesicles as a miRNA delivery carrier for the treatment of Mutidrug Resistant EndophthalmitisIndian Council of Medical Research 2024-2027 Dr Joveeta Joseph
13 Proof of Concept study of effects of Plazomicin on Islotes from Bacterial Keratitis and /or ConjuctivitisCIPLA 2023-2025 Dr Joveeta Joseph
14J C BoseScience and Engineering Research Board2023-2028Dr Mohammad Javed Ali
15Role of TET family proteins in Retinoblastoma Indian Council of Medical Research 2023-2026Dr Mamatha Reddy
16Fatty Acid desaturrase inhibition as a therapeutic statergy to restrict retinoblastoma tumor cell growth and proliferation Indian Council of Medical Research 2024- 2027Dr Mamatha Reddy
17New therapeutic approach for corneal dystrophy via CRISPR mediated SLC4A11 gene correction in an in-vitro and in-vivo system using advanced cRGD decorated lipo-polymeric nanoplexesScience and Engineering Research Board 2024-2027Dr Muralidhara Ramappa
18An Evaulation of the effectivness of contact lenses utilising S.T.O.P technology in slowing dowm myopia progression STOP 2022-2025Dr Pavan K. Verkicharla
19WOMBAT- Spectacle Film StudyNTHALMIC PVT LTD 2024-2026Dr Pavan K. Verkicharla
20 Baby Vision Screener (BaViS): A device to screen visual cognitive milestones in early childhoodIndian Council of Medical Research 2023-2025Dr PremNandhini Satgunam
21 Development of Automated Gaze Detection of Babies to study Visual Cognition Department of Biotechnology 2024-2027 Dr Prem Nandhini Satgunam
22 Artificial Intelligence enabled referral pathways for early diagnosis of complications arising from diabetes: application to diabetic retinopathyIndian Council of Medical Research 2024-2027Dr Padmaja K Rani
23Biological and molecular understanding of chemotherapy resistance and metastasis in Retinoblastoma Ramalingaswami re entry Fellowship 2024-2027Dr Pallavi Rani
24Therapeutic and immunomodulatoryeffects of human limbus-derivedmesenchymal stem cells in a rat model ofallergic conjunctivitis Indian Council of Medical Research 2023-2026Dr Pragnya Rao
25Biomimetic corneal patch for treating fungal keratitisIndian Council of Medical Research 2023-2026 Dr Prashant Garg
26Exploring potential interplay of tear cytokine levels and confocal biomicroscopy in progressive keratoconus for better clinical diagnosis-SRGScience and Engineering Research Board2024-2026Dr Rashmi Deshmukh
27 Cell-based therapy for lacrimal gland regeneration and repair in a preclinical animal model of aqueous deficiency dry eye disease Wellcome Trust India Alliance-Early Career2023-2028 Dr Swati Singh
28Preclinical development of long acting subconjuncyival steriod sparing agent to treat posterior uveitisIndian Council of Medical Research 2023-2026Dr Soumyava Basu
29Understanding the role of gasdermin D in the pathogenesis of mucormycosis-CRG Science and Engineering Research Board2023-2026Dr Sanhita Roy
30Rational design and structure-function analysis of antimicrobial peptides tailored to treat fungal ocular infections Velux Stiftung Foundation-Switerland 2023-2026Dr Sanhita Roy
31 Adult Mesenchymal stem cells as adjuctive therapy for bacterial keratitis: A novel approach to treat corneal infections Indian Council of Medical Research 2022-2025Dr Sachin Shukla
32Vision loss, disability, and multimorbidity among the elderly population in Telangana, India - The Longitudinal Eye Health Aging and Disability Study (LEADS)Wellcome Trust India Alliance2023-2028Dr Srinivas Marmamula
33 Exploring variation in humans ability to free -fuse targets for cyclopean visual experience DST- Cognitive Science Research Initiative 2023-2026Dr Shrikant Bharadwaj
34Tensor-based Machine Learning for Early Detection of Keratoconus AI4ICPS2024-2026Dr Shrikant Bhadrawaj
35 NAYAM Innovations NAYAM2025-2026Dr Shrikant Bhadrawaj
36 Biomimetic hydrogel for the treatment of blinding corneal diseasesSREE PVF2022-2025Dr Sayan Basu
37 Improving Corneal Healing Via Modulation of Tissues Ulverscroft Foundation2019-2026Dr Sayan Basu
38Corneal Characterization under biaxial loading in physiological conditions-CRGScience and Engineering Research Board2023-2026Dr Sayan Basu
39A device based on digital photo elasticity for in-vivo characterization of corneal birefringence Department of Biotechnology 2024-2027Dr Sayan Basu
40 Investigating the potential cross talk between mitochondrial and nuclear gene in primary open angle glaucomaIndian Council of Medical Research 2023-2026Dr Subhabrata Chakrabarti
41Therapeutic potential of decellularized cornea matrix (DCM) hydrogel for corneal scars and stromal replacement in trauma conditions: Pre-clinical studyIndian Council of Medical Research 2022-2025Dr Vivek Singh
42 Preclinical and phase 0/1 clinical investigation of minimally invasive microneedle patch for effective chemotherapy in Retinoblastoma Indian Council of Medical Research 2023-2026Dr Vishal R Raval
43 Development of multimodal optical coherence tomography ultrasound MEMS technology-based microscopic-resolution photo acoustic elastography (OCT-US-MEMS-μPAE) imaging system: a validation study for ophthalmic diagnosis and therapeutic treatments Department of Biotechnology 2024-2027Dr Vishal Raval
44Subretinal Fluid in Coats’ Disease: Biochemical composition and association of lipid-laden macrophages with inflammatory biomarkers Jack McGovern Coats' Disease Foundation 2024-2025Dr Vishal Raval