Basic Research

Basic Research - KAR & MTC Campus

S. No. Title Funding Agency Duration Principal Investigator
1 Effect of maternal diabetes during pregnancy on placental epigenetics and its association with retinal development and risk of retinopathy in infantsWellcome Trust India Alliance early career fellowship2024-2029Dr Aatish Mahajan
2Impact of Urban Air Pollution on ocular surface microbiome changes and its effect on dry eye disease Indian Council of Medical Research 2021-2025Dr Arunasri Kotakonda
3Mitochondrial Association with Transcriptomic Signatures for Trabecular Meshwork Damage in Glaucoma: A tissue-specific omics approach Indian Council of Medical Research 2025-2027Dr Aparna Rao
4 Setting up pathogen surveillance systems beyond SARS-CoV2 Rockefeller Foundation2022-2025Dr Bhupesh Bagga
5 Role of TRP ion channels in regulating corneal endothelial response to increased intraocular pressure Science and Engineering Research Board2023-2026Dr Charanya Ramachandran
6Silk Fibroin carrier for the culture and transplantation of corneal endotheliumDepartment of Biotechnology 2024-2027 Dr Charanya Rmachandran
7Identification of diagnostic biomarkers in vitreous/ aqueous fluid of ocular tuberculosis patients.Indian Council of Medical Research 2023-2026 Dr Himanshu Behera
8Investigating a crystiInvestigating a-crystallin-particulate matter interactions to assess the impact of air pollution on ocular protein homeostasis Indian Council of Medical Research 2023-2026Dr Inderjeet Kaur
9Development of intraocular implant providing controlled and localized combination drug therapy- towards efficacious treatment of diabetic retinopathyIndian Council of Medical Research 2023-2026Dr Inderjeet Kaur
10 Sustained dual drug release of Timolol Maleate and Latanoprost for Glaucoma Treatment: In vivo studies towards cross-linker free drug-polymer formulation for usage as eye drop Indian Council of Medical Research 2025-2028Dr Inderjeet Kaur
11Generation and evaluation of universal donor stem cells for applications in allogenic cell therapy for retinal dystrophic conditions Indian Council of Medical Research 2022-2025 Dr Indumathi Mariappan
12 Clinical utility of Extracellular Vesicles as a miRNA delivery carrier for the treatment of Mutidrug Resistant EndophthalmitisIndian Council of Medical Research 2024-2027 Dr Joveeta Joseph
13 Proof of Concept study of effects of Plazomicin on Islotes from Bacterial Keratitis and /or ConjuctivitisCIPLA 2023-2025 Dr Joveeta Joseph
14J C BoseScience and Engineering Research Board2023-2028Dr Mohammad Javed Ali
15Role of TET family proteins in Retinoblastoma Indian Council of Medical Research 2023-2026Dr Mamatha Reddy
16Fatty Acid desaturrase inhibition as a therapeutic statergy to restrict retinoblastoma tumor cell growth and proliferation Indian Council of Medical Research 2024- 2027Dr Mamatha Reddy
17New therapeutic approach for corneal dystrophy via CRISPR mediated SLC4A11 gene correction in an in-vitro and in-vivo system using advanced cRGD decorated lipo-polymeric nanoplexesScience and Engineering Research Board 2024-2027Dr Muralidhara Ramappa
18An Evaulation of the effectivness of contact lenses utilising S.T.O.P technology in slowing dowm myopia progression STOP 2022-2025Dr Pavan K. Verkicharla
19WOMBAT- Spectacle Film StudyNTHALMIC PVT LTD 2024-2026Dr Pavan K. Verkicharla
20 Baby Vision Screener (BaViS): A device to screen visual cognitive milestones in early childhoodIndian Council of Medical Research 2023-2025Dr PremNandhini Satgunam
21 Development of Automated Gaze Detection of Babies to study Visual Cognition Department of Biotechnology 2024-2027 Dr Prem Nandhini Satgunam
22 Artificial Intelligence enabled referral pathways for early diagnosis of complications arising from diabetes: application to diabetic retinopathyIndian Council of Medical Research 2024-2027Dr Padmaja K Rani
23Biological and molecular understanding of chemotherapy resistance and metastasis in Retinoblastoma Ramalingaswami re entry Fellowship 2024-2027Dr Pallavi Rani
24Evaluation and Characterization of Tear-Derived Small Extracellular Vesicles for Prognostication and Genetic Insights in Retinoblastoma Anusandhan National Research Foundation2025-2028Dr Pallavi Rani
25Therapeutic and immunomodulatoryeffects of human limbus-derivedmesenchymal stem cells in a rat model ofallergic conjunctivitis Indian Council of Medical Research 2023-2026Dr Pragnya Rao
26Biomimetic corneal patch for treating fungal keratitisIndian Council of Medical Research 2023-2026 Dr Prashant Garg
27 Antibiotic loaded corneal device: A platform delivery system to tackle ophthalmic infectionsVelux Stiftung 2025-2028 Dr Prashant Garg
28Ecofriendly Biofilm Inhibiting Coatings on Hernia Repair Meshes for Prevention of Surgical Site InfectionsDepartment of Science and Technology2025-2027 Dr Prashant Garg
29Centre for Advanced Research in Ocular Drug Delivery Devices: Developing Stable Platforms for Extemporaneous Antimicrobials to Counteract Antimicrobial Resistance (AMR) Indian Council of Medical Research 2025-2028 Dr Prashant Garg
30Exploring potential interplay of tear cytokine levels and confocal biomicroscopy in progressive keratoconus for better clinical diagnosis-SRGScience and Engineering Research Board2024-2026Dr Rashmi Deshmukh
31 Cell-based therapy for lacrimal gland regeneration and repair in a preclinical animal model of aqueous deficiency dry eye disease Wellcome Trust India Alliance-Early Career2023-2028 Dr Swati Singh
32Preclinical development of long acting subconjuncyival steriod sparing agent to treat posterior uveitisIndian Council of Medical Research 2023-2026Dr Soumyava Basu
33Understanding the role of gasdermin D in the pathogenesis of mucormycosis-CRG Science and Engineering Research Board2023-2026Dr Sanhita Roy
34Rational design and structure-function analysis of antimicrobial peptides tailored to treat fungal ocular infections Velux Stiftung Foundation-Switerland 2023-2026Dr Sanhita Roy
35 Adult Mesenchymal stem cells as adjuctive therapy for bacterial keratitis: A novel approach to treat corneal infections Indian Council of Medical Research 2022-2025Dr Sachin Shukla
36Vision loss, disability, and multimorbidity among the elderly population in Telangana, India - The Longitudinal Eye Health Aging and Disability Study (LEADS)Wellcome Trust India Alliance2023-2028Dr Srinivas Marmamula
37 Exploring variation in humans ability to free -fuse targets for cyclopean visual experience DST- Cognitive Science Research Initiative 2023-2026Dr Shrikant Bharadwaj
38Tensor-based Machine Learning for Early Detection of Keratoconus AI4ICPS2024-2026Dr Shrikant Bhadrawaj
39 NAYAM Innovations NAYAM2025-2026Dr Shrikant Bhadrawaj
40Investigating the static and dynamic Characteristics of accommodation as a marker to differentiate “pseudo myopia from true axial myopia Essilor Essilor Corporation2025-2027Dr Shrikant Bhadrawaj
41 Biomimetic hydrogel for the treatment of blinding corneal diseasesSREE PVF2022-2025Dr Sayan Basu
42 Improving Corneal Healing Via Modulation of Tissues Ulverscroft Foundation2019-2026Dr Sayan Basu
43Corneal Characterization under biaxial loading in physiological conditions-CRGScience and Engineering Research Board2023-2026Dr Sayan Basu
44A device based on digital photo elasticity for in-vivo characterization of corneal birefringence Department of Biotechnology 2024-2027Dr Sayan Basu
45To investigate limbal biology in Stevens-Johnson Syndrome (SJS) and develop various animal models of SJS pathology. Velux Stiftung 2025-2029Dr Sayan Basu
463D Bioprinted Corneal Stroma for Partial Keratoplasty: A Step Toward Restoring VisionIndian Council of Medical Research - First in the world2025-2028Dr Sayan Basu
47Phase I/II Multicenter Randomized Controlled Clinical Trial of Mesenchymal Stem Cell Therapy for Severe Ocular Surface Chemical injury - University of Illinois- Chicago University of Illinois - Chicago 2024-2026Dr Sayan Basu
48 Investigating the potential cross talk between mitochondrial and nuclear gene in primary open angle glaucomaIndian Council of Medical Research 2023-2026Dr Subhabrata Chakrabarti
49Therapeutic potential of decellularized cornea matrix (DCM) hydrogel for corneal scars and stromal replacement in trauma conditions: Pre-clinical studyIndian Council of Medical Research 2022-2025Dr Vivek Singh
50Biomaterial and cell based therapy for corneal blindnessDepartment of Biotechnology ( TATA innovation program) 2024-2027Dr Vivek Singh
51 Preclinical and phase 0/1 clinical investigation of minimally invasive microneedle patch for effective chemotherapy in Retinoblastoma Indian Council of Medical Research 2023-2026Dr Vishal R Raval
52 Development of multimodal optical coherence tomography ultrasound MEMS technology-based microscopic-resolution photo acoustic elastography (OCT-US-MEMS-μPAE) imaging system: a validation study for ophthalmic diagnosis and therapeutic treatments Department of Biotechnology 2024-2027Dr Vishal Raval
53Subretinal Fluid in Coats’ Disease: Biochemical composition and association of lipid-laden macrophages with inflammatory biomarkers Jack McGovern Coats' Disease Foundation 2024-2025Dr Vishal Raval